Describe the expression pattern of Dll3 in the presomitic mesoderm and first somite. Comment on the cyclical pattern of expression (if any). (A) (B) (C) (D) Rostral Somite SO SI SO SI SO SI SII SO SI SII Region of Hairyl expression 2.What is the impact of a D113 mutation on expression pattern of the cycling genes during one round of somitogenesis? Caudal 90 minutes (one somite forms) 3. Describe the phenotype of humans with DLL3 mutations?

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